Specialist information for healthcare professionals

Introducing CB12 safe breath rinse and boost gum

Developed by dentists, CB12 rinse is a unique mouthwash that offers a lasting solution to bad breath.1 Unlike other oral hygiene products, it doesn't just mask bad breath - CB12's clinically proven formulation neutralises and prevents the cause of the problem for 12 hours with just one use.

The active ingredients in CB12 - Zinc and Chlorhexidine - neutralise the volatile sulphurous compound (VSC) gases that cause bad breath, without killing oral bacteria that are a natural part of digestion.1-2

  • Clinically proven: more effective against bad breath than 18 leading mouthwashes2-3
  • Unique patented formulation: neutralises the sulphurous gases that cause bad breath1-2
  • 12 hour effect from the first use: adheres to mouth surfaces for lasting results1
  • Contains fluoride: to protect teeth from decay

New CB12 boost gum:

  • Superior and unique triple action formula with zinc, fluoride and xylitol
  • Prevents bad breath, strengthens teeth and reduces plaque for customers who prefer gum to mouth rinse

Causes of bad breath

The most common type of bad breath is known as 'endogenous', which is caused by factors within the oral cavity, like gingivitis. This differs to bad breath caused by external factors, which is called 'exogenous' and can be due to eating foods such as garlic.

Endogenous bad breath can have several causes, but in most cases it's caused by bacteria in the mouth breaking down bits of food into bad-smelling gaseous sulphur compounds, which are then perceived as bad breath. Since all people have these bacteria in the mouth, it's possible for anyone to develop bad breath.

Some low carbohydrate and crash diets can also increase bad breath because they cause the body to break down fat, which produces chemicals called ketones that can be smelt on the breath.

Other causes of bad breath can include poor oral hygiene, inflammation of the gums (gingivitis), loosening of the teeth (periodontitis), stress, dry mouth and infections in the lungs, throat or nose, bronchitis, sinusitis, diabetes, liver or kidney problems and gastritis (inflammation of the lining of the stomach). Taking certain drugs can have side effects that cause bad breath.4


Scientifically proven to work

CB12 rinse

Available in 50ml, 250ml and 1L bottles, CB12 rinse has been developed by dentists according to rigorous scientific methods. CB12 rinse's unique combination of Zinc and Chlorhexidine is proven to have a 'synergistic' effect - working together to provide a long-lasting neutralising effect on bad breath.3,5

  • Rigorously tested: in clinical studies using gas chromatography breath analysis, organoleptic testing and a specially developed halimeter
  • Clinically proven: more effective against bad breath than 18 leading mouthwashes2-3
  • Unique patented formulation: the first of its kind to neutralise all three of the VSCs (volatile sulphur compounds) that cause bad breath6
  • Zinc acetate works in synergy with Chlorhexidine to effectively neutralise bad breath-causing sulphur compounds3,5
  • Chlorhexidine diacetate breaks down even complex VSC gases, and adheres to mouth surfaces for a 12-hour lasting effect1,5

CB12 boost chewing gum

Chewing gum containing zinc is able to reduce and inhibit the formation of VSCs (hydrogen sulphide, metyl mercaptan & dimethyl sulphide) in the oral cavity, which results in fresher breath. 

In CB12 Zinc acetate was chosen as the source of zinc because it proved to be best suitable for releasing free Zn2+ in aqueous solution. Zinc is found in various forms; zinc acetate, zinc gluconate (with a low stability constant; ie easily soluble in water) and zinc citrate and zinc lactate (medium stability constant) and zinc amino acid chelate (very high stability constant). The zinc ions are effective against halitosis, releasing from the chewing gum to form stable mercaptides with VSCs, since zinc has an affinity for sulphur and oxidizes sulfhydryl groups. 

Download your professionals pack

Professional pack

  • Consumer leaflet
  • Healthcare professional leaflet
  • Frequently asked questions
  • In-store poster


  1. Thrane PS, et al, Dental Health 2009; 48(3):8-12.
  2. Thrane PS, et al, J Clin Dent 2007; 18(3):82-87.
  3. Thrane PS, et al, Dental Health 2010; 49(1):6-10.
  4. Young A, et al, International Dental Journal 2003; 53:237-242.
  5. NHS Choices website:  (Accessed October 2012).
  6. ICM Market Research conducted amongst 2024 consumers, August 2012. 

- Please contact your dentist or pharmacist, or go to CB12 homepage for further information

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